Groundbreaking Discovery in Pharmacogenomics!
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BIG BREAKING NEWS 🎊🎊 – A Groundbreaking Discovery in Pharmacogenomics! First Report on Genetic Polymorphism rs2257212 and Its Role in Colistin-Induced Nephrotoxicity We are thrilled to announce an extraordinary breakthrough in medical genetics! 🎉 Dr. Sumith Mathew , with the technical support of Dr. C. C. Cleetus , has achieved a milestone in precision medicine by identifying a novel association between genetic polymorphisms and colistin-induced nephrotoxicity. Their study, published under PMC10933594 , marks the first-ever report on the role of two key genetic polymorphisms— rs2257212 and rs13397109 —in the context of nephrotoxicity caused by colistin, a last-resort antibiotic used to treat multidrug-resistant infections. Key Findings of the Study 🔬 Among the two polymorphisms studied, rs2257212 , located in the SLC15A2 gene, exhibited a stronger correlation with nephrotoxicity. This gene encodes the PEPT2 (solute carrier family 15 member 2) protein , which plays a cr...