Believers Church Medical College Hospital

  BIG BREAKING NEWS 🎊🎊 – A Groundbreaking Discovery in Pharmacogenomics! First Report on Genetic Polymorphism rs2257212 and Its Role in Colistin-Induced Nephrotoxicity We are thrilled to announce an extraordinary breakthrough in medical genetics! 🎉 Dr. Sumith Mathew , with the technical support of Dr. C. C. Cleetus , has achieved a milestone in precision medicine by identifying a novel association between genetic polymorphisms and colistin-induced nephrotoxicity. Their study, published under PMC10933594 , marks the first-ever report on the role of two key genetic polymorphisms— rs2257212 and rs13397109 —in the context of nephrotoxicity caused by colistin, a last-resort antibiotic used to treat multidrug-resistant infections. Key Findings of the Study 🔬 Among the two polymorphisms studied, rs2257212 , located in the SLC15A2 gene, exhibited a stronger correlation with nephrotoxicity. This gene encodes the PEPT2 (solute carrier family 15 member 2) protein , which plays a cr...

  Journal Club – Advancing Research in Dengue Shock Pathophysiology 📢 Exciting Research Discussion at Central Research Laboratory (CRL), BCMCH! Join us for an insightful Journal Club session as we delve into the latest research on endothelial and inflammatory pathophysiology in dengue shock . This session will explore groundbreaking findings from a prospective cohort study conducted in Vietnam —shedding light on critical mechanisms that influence disease progression and patient outcomes. 🔹 Event Details: 📅 Date: 28th March 2025 ⏰ Time: 3:00 PM 📍 Venue: Central Research Laboratory, BCMCH 🎤 Presenter: 👩‍🔬 Ms. Praseeda Prasad 🏥 CRL, BCMCH 🔬 Key Highlights: ✅ Understanding endothelial dysfunction in dengue shock ✅ Role of inflammatory responses in disease severity ✅ Implications for clinical management and therapeutic strategies ✅ Discussion on recent findings from a large-scale study in Vietnam 🔬 Why Attend? ✔ Enhance your knowledge of critical pathophysi...

  Exploring the Role of Gut Bacteria in Antibiotic Secretion – Journal Club at CRL, BCMCH The Central Research Laboratory (CRL) at Believers Church Medical College Hospital (BCMCH) recently hosted an engaging Journal Club session on March 14, 2025 . The event provided an excellent platform for faculty and researchers to discuss groundbreaking scientific discoveries and their implications for medical advancements. Topic of Discussion: Bile Acid 7α-Dehydroxylating Gut Bacteria & Clostridium difficile Inhibition The session featured an insightful presentation by Mr. Adithya P Kumar (CRL, BCMCH) on the topic: 🔬 "Bile Acid 7α-Dehydroxylating Gut Bacteria Secrete Antibiotics that Inhibit Clostridium difficile: Role of Secondary Bile Acids." This research delves into the critical role of gut microbiota in inhibiting pathogenic bacterial infections by producing secondary bile acids with antibiotic properties. The study is particularly relevant in the context of Clostrid...

  National Level Scientific Session – “Research to Reality” Organized by Central Research Laboratory, Believers Church Medical College Hospital (BCMCH) 28th September 2024 The Central Research Laboratory (CRL) of Believers Church Medical College Hospital (BCMCH) successfully hosted a National Level Scientific Session titled “Research to Reality – Journey from Theoretical Research to Real World Applications” on 28th September 2024. This event was designed to provide a platform for discussing the vital process of translating innovative research into practical, real-world solutions, with a particular focus on healthcare and societal impact. Objective and Focus The theme of the event, “Research to Reality,” aimed to highlight the journey from conducting theoretical research to implementing those findings in real-world applications. The goal was to bridge the gap between academic knowledge and practical solutions that benefit society. Researchers, scientists, faculty, and students fro...